Influence of short- and long-term administration of Melengestrol acetate on estrus activity and reproductive performance of nulliparous Barki ewes

In Egypt, research focusing on estrous synchronization in small ruminants based on Melengestrol acetate (MGA) supplementation, particularly in nulliparous ewes, is still lacking. The present work aimed to evaluate effect of long-term and short-term administration of melengestrol acetate (MGA) treatments on estrus synchronization and reproductive performance of nulliparous Barki Ewes. This study was performed in Siwa Oasis Research Station (Tegzerty Experimental Farm for animal production), belonged to Desert Research Center, Egypt. Forty five nulliparous Barki ewes with age ranging from 15.5 to 16.5 months, and 38 ± 0.23 kg average live body weight were assigned to one of three groups: (1) control (C, n = 15); (2) long-term treatment with MGA (n = 15, 0.22 mg/ewe/d for 14 days) and (3) short-term treatment with MGA (n = 15, 0.22 mg/ewe/d for 7 days). At the end of MGA treatment (14 or 7 d) all treated ewes were injected by 600 IU PMSG intramuscularly. The results showed that, ewes treated with MGA exhibited highest (

Reducing Onion Bulbs Flaking and Increasing Bulb Yield and Quality by Potassium and Calcium Application

Abstract: To investigate the onion bulb flaking during storage in order to increase exportation, a two field experiments were conducted during winte

Cognitive neuroscience of delusions in aging

Assessments and clinical understanding of late-onset delusions in the elderly are inconsistent and often incomplete. In this review, we consider the prevalence, neurobehavioral features, and neuroanatomic correlations of delusions in elderly persons – those with documented cognitive decline and those with no evidence of cognitive decline. Both groups exhibit a common phenotype: delusions are either of persecution or of misidentification. Late-onset delusions show a nearly complete absence of the grandiose, mystical, or erotomanic content typical of early onset psychoses. Absent also from both elderly populations are formal thought disorders, thought insertions, and delusions of external control. Neuroimaging and behavioral studies suggest a frontotemporal localization of delusions in the elderly, with right hemispheric lateralization in delusional misidentification and left lateralization in delusions of persecution. We propose that delusions in the elderly reflect a common neuroanatomic and functional phenotype, and we discuss applications of our proposal to diagnosis and treatment

Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemic

<p>Abstract</p> <p>Background</p> <p>Follow-up epidemiologic studies are needed to assess trends and patterns of disease spread. No follow-up epidemiologic study has been done in the Kingdom of Saudi Arabia to assess the current prevalence of major chronic, noncommunicable diseases, specifically in the urban region, where modifiable risk factors remain rampant. This study aims to fill this gap.</p> <p>Methods</p> <p>A total of 9,149 adult Saudis ages seven to eighty years (5,357 males (58.6%) and 3,792 females (41.4%)) were randomly selected from the Riyadh Cohort Study for inclusion. Diagnosis of type 2 diabetes mellitus (DMT2) and obesity were based on the World Health Organization definitions. Diagnoses of hypertension and coronary artery disease (CAD) were based on the Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and American Heart Association criteria, respectively.</p> <p>Results</p> <p>The overall crude prevalence of DMT2 was 23.1% (95% confidence interval (95% CI) 20.47 to 22.15). The age-adjusted prevalence of DMT2 was 31.6%. DMT2 prevalence was significantly higher in males, with an overall age-adjusted prevalence of 34.7% (95% CI 32.6 to 35.4), than in females, who had an overall age-adjusted prevalence of 28.6% (95% CI 26.7 to 29.3) (<it>P </it>< 0.001). The overall crude prevalence of obesity was 31.1% (95% CI 30.1 to 32.0). The age-adjusted prevalence of obesity was 40.0%. The prevalence of obesity was higher in females, with an overall prevalence of 36.5% (95% CI 35.1 to 37.83), than in males (25.1% (95% CI 23.7 to 26.3)) (<it>P </it>< 0.001). The age-adjusted prevalence of hypertension and CAD were 32.6% (95% CI 31.7 to 33.6) and 6.9% (95% CI 6.4 to 7.4), respectively.</p> <p>Conclusion</p> <p>Comparisons of our findings with earlier data show that the prevalence of DMT2, hypertension and CAD in Riyadh, Saudi Arabia, has alarmingly worsened. Aggressive promotion of public awareness, continued screening and early intervention are pivotal to boosting a positive response.</p

Regional research priorities in brain and nervous system disorders

The characteristics of neurological, psychiatric, developmental and substance-use disorders in low-and middle-income countries are unique and the burden that they have will be different from country to country. Many of the differences are explained by the wide variation in population demographics and size, poverty, conflict, culture, land area and quality, and genetics. Neurological, psychiatric, developmental and substance-use disorders that result from, or are worsened by, a lack of adequate nutrition and infectious disease still afflict much of sub-Saharan Africa, although disorders related to increasing longevity, such as stroke, are on the rise. In the Middle East and North Africa, major depressive disorders and post-traumatic stress disorder are a primary concern because of the conflict-ridden environment. Consanguinity is a serious concern that leads to the high prevalence of recessive disorders in the Middle East and North Africa and possibly other regions. The burden of these disorders in Latin American and Asian countries largely surrounds stroke and vascular disease, dementia and lifestyle factors that are influenced by genetics. Although much knowledge has been gained over the past 10 years, the epidemiology of the conditions in low-and middle-income countries still needs more research. Prevention and treatments could be better informed with more longitudinal studies of risk factors. Challenges and opportunities for ameliorating nervous-system disorders can benefit from both local and regional research collaborations. The lack of resources and infrastructure for health-care and related research, both in terms of personnel and equipment, along with the stigma associated with the physical or behavioural manifestations of some disorders have hampered progress in understanding the disease burden and improving brain health. Individual countries, and regions within countries, have specific needs in terms of research priorities.Fil: Ravindranath, Vijayalakshmi. Indian Institute of Science; IndiaFil: Dang, Hoang Minh. Vietnam National University; VietnamFil: Goya, Rodolfo Gustavo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata ; ArgentinaFil: Mansour, Hader. University of Pittsburgh; Estados Unidos. Mansoura University; EgiptoFil: Nimgaonkar, Vishwajit L.. University of Pittsburgh; Estados UnidosFil: Russell, Vivienne Ann. University of Cape Town; SudáfricaFil: Xin, Yu. Peking University; Chin

Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children &lt;18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p&lt;0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p&lt;0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p&lt;0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer

Effect of compost and natural rocks as partial substitutes for NPK mineral fertilizers on yield and fruit quality of ‘Flame’ seedless grapevine grown in two different locations of Egypt

Aim of study: To evaluate the use of compost and natural rocks as partial replacement of mineral fertilizers in ‘Flame’ seedless grape vineyards.Area of study: The present work was conducted during three successive seasons (2016, 2017 and 2018), being the first season a preliminary trial on 4-yr old grapes cultivated in two different soil types (sandy and clay) at two different locations, Egypt (Abo Galeb, Giza governorate; EL-Mahala, Gharbia governorate).Material and methods: Treatments were applied as natural raw materials at 20, 40, 60, 80 and 100% out of recommended mineral NPK rate. The mineral fertilizers used were ammonium sulfate (21.6% N), calcium super phosphate (15.5% P2O5) and potassium sulfate (48% K2O). The natural rocks used were phosphate rock (22.0% P2O5) and Feldspar (10.12% K2O). Yield and fruit characteristics and leaf mineral content were determined.Main results: Using compost in combination with natural rocks enriched with NPK mobilization bacteria and mineral NPK enhanced leaf nutrients content and gave the highest yield and cluster weight. This mix also improved berries physical and chemical characteristics. There was an increase in soluble solids content (SSC), SSC/acid ratio, and anthocyanin content, associated with a reduction in nitrate content of the berry juice. The most pronounced effect was related to using 60% mineral fertilization + 40% organic and natural rocks in both vineyard locations.Research highlights: We can reduce the recommended doses of mineral NPK by about 40%, reducing then the soil pollution

مؤشرات أداء التجارة الخارجية الزراعية العربية

The foreign trade has important implications on economic development. The most important implication in this regard is the development of exports towards reduction of the trade deficit and improving the terms of trade. In addition, when the national economy holds considerable agricultural resources, the foreign trade policies become key issues in the development program towards achieving considerable self-sufficiency rates for major food groups. In this context the study aimed at conducting an analytical study of the agricultural foreign trade performance over the past two decades through some major relevant indicators. The study relied on published data from relevant regional and international organizations and relevant studies. Low share of the Arab states' agricultural exports in the global market indicated that the vulnerability of the Arabic market with the global market was much higher than the degree of influence. The total value of commodity exports of 21 Arab countries was less than 5% of the total volume of world merchandise exports. Such value contained oil exports during the period 2004-2011. The Arabic States with large agricultural resources that had the highest share in the world merchandise exports, were also exporting oil. Such countries included Sudan, with a share of 0.52% and Egypt with a share of 0.2%. Therefore, the individual Arabic countries rush to join individually the World Trade Organization had made their economies prey to the rigid terms of trade liberalization. If they were joined the °organization as a common market, they would be able to get some privileges or ease the burden of the conditions that many of them have shown inability to meet them. The market share of agricultural commodity exports of Arab states did not exceed 1% of the agricultural commodity exports in the global market. While total merchandise exports had achieved on average a trade surplus of 45% (2004-2008), there was deterioration in such surplus to 13% in 2011, the average Arab agricultural exports covered only 24% over the period 2004-2008 and dropped to 20% in 2011. This low rate of coverage was consistent with the poor performance of the Arab agricultural trade in other measured indicators and as a result of the slow growth of II e Arabic agricultural exports versus accelerated world agricultural market growth. Fish and vegetable group, unlike the rest of the commodity groups, had achieved surplus during period (2004-2011), despite fluctuating in such surplus rate. There were two profound food commodities groups that achieved a surplus in exports value above imports. These were e fruits and tubers (potatoes). Although Arab self-sufficiency ratio above 100% in fruits and legumes, their exports value covered only 85%of their imports, indicating a failure of terms of trade, i.e. the average unit value of exports, were higher than the average unit value of imports,. The export policies succeeded partially in some food commodities, the agricultural policies of the Arab States have generally failed to develop the foreign trade performance. The empirical evidence was that the terms of trade indices gave a positive result in five years in only one country (Palestine), followed by Algeria (in three years), the remainder of the Arab countries have achieved this result just either in two separate years or only in one yea